Article
Enhancement of Pathologist's Routine Practice: Reuse of DNA Extracted from Immunostained Formalin-fixed Paraffin-embedded (FFPE) Slides in Downstream Molecular Analysis of Cancer.
Cancer genomics & proteomics - 1 Jan 2000
Al-Attas Asmaa, Assidi Mourad, Al-Maghrabi Jaudah, Dallol Ashraf, Schulten Hans-Juergen, Abu-Elmagd Muhammad, Chaudhary Adeel, Abuzenadah Adel, Budowle Bruce, Buhmeida Abdelbaset, Al-Qahtani Mohammed
Abstract excerpt
BACKGROUND/AIM: To date, the conventional formalin-fixed, paraffin-embedded (FFPE) technique is the gold-standard for preserving histomorphology. Once FFPE tissues are stained, slides are routinely archived along with their blocks at biobanks/hospitals. However, the reuse of fixed and stained biospecimens as DNA source is not a common routine practice worldwide and, thus, indicates the need of studies to...
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