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Article

Potential of DNA methylation in rectal cancer as diagnostic and prognostic biomarkers

1 Sept 2015

Abstract excerpt

BACKGROUND: Aberrant DNA methylation is more prominent in proximal compared with distal colorectal cancers. Although a number of methylation markers were identified for colon cancer, yet few are available for rectal cancer. METHODS: DNA methylation differences were assessed by a targeted DNA microarray for 360 marker candidates between 22 fresh frozen rectal tumour samples and 8 controls and validated by...

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Share to Colorectal Cancer Screening and Detection
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Identifiers

PMID: 26335606
DOI: 10.1038/bjc.2015.303

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