Article
Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.
Neurology - 22 Apr 2014
Carrasquillo Minerva M, Khan Qurat ul Ain, Murray Melissa E, Krishnan Siddharth, Aakre Jeremiah, Pankratz V Shane, Nguyen Thuy, Ma Li, Bisceglio Gina, Petersen Ronald C, Younkin Steven G, Dickson Dennis W, Boeve Bradley F, Graff-Radford Neill R, Ertekin-Taner Nilüfer
Abstract excerpt
OBJECTIVE: To investigate association of genetic risk factors for late-onset Alzheimer disease (LOAD) with risk of posterior cortical atrophy (PCA), a syndrome of visual impairment with predominant Alzheimer disease (AD) pathology in posterior cortical regions, and with risk of "posterior AD" neuropathology. METHODS: We assessed 81 participants with PCA diagnosed clinically and 54 with neuropathologic diagnosis...
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