Article
Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2013
Tan Lan, Yu Jin-Tai, Zhang Wei, Wu Zhong-Chen, Zhang Qun, Liu Qiu-Yan, Wang Wei, Wang Hui-Fu, Ma Xiao-Ying, Cui Wei-Zhen
Abstract excerpt
OBJECTIVE: Five genomewide association studies (GWAS) in white populations have recently identified and confirmed 9 novel Alzheimer's disease (AD) susceptibility loci (CLU, CR1, PICALM, BIN1, ABCA7, MS4A gene cluster, CD2AP, CD33, and EPHA1). These studies have been conducted almost exclusively in white populations and it is unclear whether these observations generalize to populations with different ethnicities....
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