Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strain-dependent modulation of macrophage polarization within scaffolds.

Biomaterials - 1 Jun 2014

Ballotta Virginia, Driessen-Mol Anita, Bouten Carlijn V C, Baaijens Frank P T

Abstract excerpt

Implanted synthetic substrates for the regeneration of cardiovascular tissues are exposed to mechanical forces that induce local deformation. Circulating inflammatory cells, actively participating in the healing process, will be subjected to strain once recruited. We investigated the effect of deformation on human peripheral blood mononuclear cells (hPBMCs) adherent onto a scaffold, with respect to macrophage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Shape
Share to Chemokine CCL2
Share to Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosaminoglycans

Share to Lactones

Share to Regeneration

Share to Tissue Scaffolds

Share to Wound Healing

Source

Identifiers

PMID: 24661551
DOI: 10.1016/j.biomaterials.2014.03.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strain-dependent modulation of macrophage polarization within scaffolds.PMID 24661551Read ↗

Macrophage Mechano-Responsiveness Within Three-Dimensional Tissue Matrix upon Mechanotherapy-Associated Strains.Semantic proximity Read ↗

Temporal Control over Macrophage Phenotype and the Host Response via Magnetically Actuated Scaffolds.Semantic proximity Read ↗

Shear Stress Induces a Time-Dependent Inflammatory Response in Human Monocyte-Derived MacrophagesSemantic proximity Read ↗

Cyclic biaxial strain affects U937 macrophage-like morphology and enzymatic activities.Semantic proximity Read ↗

Substrate stiffness directs the phenotype and polarization state of cord blood derived macrophages.Semantic proximity Read ↗

Human <i>in vitro</i> model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formationSemantic proximity Read ↗

Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory SubpopulationsSemantic proximity Read ↗

The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold architectures.Semantic proximity Read ↗

Viscoelastic Hydrogel Modulates Phenotype of Macrophage-Derived Multinucleated Cells and Macrophage Differentiation in Foreign Body Reactions.Semantic proximity Read ↗

The Effect of Mechanical Stimuli on the Phenotypic Plasticity of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells in a 3D HydrogelSemantic proximity Read ↗

Novel 3-D macrophage spheroid model reveals reciprocal regulation of immunomechanical stress and mechano-immunological responseSemantic proximity Read ↗

In vitro modulation of the behavior of adhering macrophages by medications is biomaterial-dependent.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.