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Article

Substrate stiffness directs the phenotype and polarization state of cord blood derived macrophages.

Acta biomaterialia - 1 Mar 2021

Scott Rebecca A, Kiick Kristi L, Akins Robert E

Abstract excerpt

Cord blood (CB) mononuclear cell populations have demonstrated significant promise in biomaterials-based regenerative therapies; however, the contributions of monocyte and macrophage subpopulations towards proper tissue healing and regeneration are not well understood, and the phenotypic responses of macrophage to microenvironmental cues have not been well-studied. In this work, we evaluated the effects of...

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PMID: 33359292
DOI: 10.1016/j.actbio.2020.12.040
PMCID: PMC7904389

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