Article
In vitro modulation of the behavior of adhering macrophages by medications is biomaterial-dependent.
Biomedical materials (Bristol, England) - 7 Mar 2017
Utomo Lizette, Boersema Geesien S A, Bayon Yves, Lange Johan F, van Osch Gerjo J V M, Bastiaansen-Jenniskens Yvonne M
Abstract excerpt
After implantation of a biomaterial, an inflammatory response involving macrophages is induced. The behavior of macrophages depends on their phenotype, and by directing macrophage polarization unwanted effects may be avoided. In this study, the possibility to modulate the behavior of macrophages activated by biomaterials was assessed in an in vitro model. Primary human monocytes were seeded on polyethylene...
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