Article
Cyclic biaxial strain affects U937 macrophage-like morphology and enzymatic activities.
Journal of biomedical materials research. Part A - 1 Jan 2006
Matheson Loren A, Maksym Geoffrey N, Santerre J Paul, Labow Rosalind S
Abstract excerpt
As monocytes migrate to the site of a foreign body and differentiate into mature monocyte-derived macrophages (MDMs), the cells undergo a morphological transformation that involves mechanical stimulation via membrane stretch. Because the site of many cardiovascular implant devices includes substrates that are also undergoing mechanical change, it is of interest to assess the effect of such dynamic conditions on...
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