Article
Temporal Control over Macrophage Phenotype and the Host Response via Magnetically Actuated Scaffolds.
ACS biomaterials science & engineering - 8 Aug 2022
Steele Lindsay A, Spiller Kara L, Cohen Smadar, Rom Slava, Polyak Boris
Abstract excerpt
Cyclic strain generated at the cell-material interface is critical for the engraftment of biomaterials. Mechanosensitive immune cells, macrophages regulate the host-material interaction immediately after implantation by priming the environment and remodeling ongoing regenerative processes. This study investigated the ability of mechanically active scaffolds to modulate macrophage function in vitro and in vivo....
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