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Human <i>in vitro</i> model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation

2019-09-05

Abstract excerpt

1 Resorbable synthetic scaffolds designed to regenerate living tissues and organs inside the body emerge as a clinically attractive technology to replace diseased blood vessels. However, mismatches between scaffold design and in vivo hemodynamic loading (i.e., cyclic stretch and shear stress) can result in aberrant inflammation and adverse tissue remodeling, leading to premature graft failure. Yet, the underlying...

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Literature Corpus work
103ab11b-b311-59a5-b366-0a2c5db0516c
DOI
10.1101/755157
Open publication

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Human <i>in vitro</i> model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formationDOI 10.1101/755157
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