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Article

Evidence for local regulatory control of escape from imprinted X chromosome inactivation.

Genetics - 1 Jun 2014

Mugford Joshua W, Starmer Joshua, Williams Rex L, Calabrese J Mauro, Mieczkowski Piotr, Yee Della, Magnuson Terry

Abstract excerpt

X chromosome inactivation (XCI) is an epigenetic process that almost completely inactivates one of two X chromosomes in somatic cells of mammalian females. A few genes are known to escape XCI and the mechanism for this escape remains unclear. Here, using mouse trophoblast stem (TS) cells, we addr...

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Identifiers

PMID: 24653000
DOI: 10.1534/genetics.114.162800
PMCID: PMC4063926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24653000-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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