The mouse Smcx gene exhibits developmental and tissue specific variation in degree of escape from X inactivation.

doi:10.1093/hmg/5.9.1355

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Article

The mouse Smcx gene exhibits developmental and tissue specific variation in degree of escape from X inactivation.

Human molecular genetics - 1 Sept 1996

Sheardown S, Norris D, Fisher A, Brockdorff N

Abstract excerpt

The Smcx gene is the first known example of a non-pseudoautosomal X-linked gene in mouse that normally escapes X chromosome inactivation. We have analysed the kinetics of escape at different stages of development, and in adult tissues. Our results demonstrate that Smcx exhibits partial escape fro...

Topics

Alleles
Animals
Female
Genetic Linkage
Histone Demethylases
Mice
Oxidoreductases, N-Demethylating
Proteins
X Chromosome

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