Article
The mouse Smcx gene exhibits developmental and tissue specific variation in degree of escape from X inactivation.
Human molecular genetics - 1 Sept 1996
Sheardown S, Norris D, Fisher A, Brockdorff N
Abstract excerpt
The Smcx gene is the first known example of a non-pseudoautosomal X-linked gene in mouse that normally escapes X chromosome inactivation. We have analysed the kinetics of escape at different stages of development, and in adult tissues. Our results demonstrate that Smcx exhibits partial escape from X inactivation in embryos, in extraembryonic lineages where paternally imprinted X inactivation occurs and also in...
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