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Article

The high-mobility group protein B1-Toll-like receptor 4 pathway contributes to the acute lung injury induced by bilateral nephrectomy.

Kidney international - 1 Aug 2014

Doi Kent, Ishizu Tomoko, Tsukamoto-Sumida Maki, Hiruma Takahiro, Yamashita Tetsushi, Ogasawara Emi, Hamasaki Yoshifumi, Yahagi Naoki, Nangaku Masaomi, Noiri Eisei

Abstract excerpt

Acute lung injury and acute kidney injury are severe complications in critically ill patients and synergistically increase mortality in intensive care units. Organ cross-talk between the kidney and the lung has been implicated recently as amplifying injury in each organ. Here we sought to identify a possible mechanism of acute kidney injury-induced acute lung injury using a mouse bilateral nephrectomy model....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24646859
DOI: 10.1038/ki.2014.62

Genes

TLR4
HMGB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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