Article

Circulating osteopontin released by injured kidneys causes pulmonary inflammation and edema

2021-07-21

Abstract excerpt

Multiorgan failure is devastating, and its mechanisms and mediators are not clear. Tissue injury in one organ appears to trigger disease in remote organs. Kidney and lung are frequently affected, such as when acute kidney injury (AKI) causes acute lung injury (ALI), a frequent clinical condition with high mortality. Here we identify factors secreted from the injured kidney that cause acute lung injury. We develope...

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Literature Corpus work: 01488955-68e7-5e78-9ae6-f3ea7c40fe08
DOI: 10.1101/2021.07.20.452998

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