Article
Pleiotropic Association of CACNA1C Variants With Neuropsychiatric Disorders.
Schizophrenia bulletin - 7 Sept 2023
Wang Zuxing, Lin Xiandong, Luo Xinqun, Xiao Jun, Zhang Yong, Xu Jianying, Wang Shibin, Zhao Fen, Wang Huifen, Zheng Hangxiao, Zhang Wei, Lin Chen, Tan Zewen, Cao Liping, Wang Zhiren, Tan Yunlong, Chen Wenzhong, Cao Yuping, Guo Xiaoyun, Pittenger Christopher, Luo Xingguang
Abstract excerpt
BACKGROUND: Neuropsychiatric disorders are highly heritable and have overlapping genetic underpinnings. Single nucleotide polymorphisms (SNPs) in the gene CACNA1C have been associated with several neuropsychiatric disorders, across multiple genome-wide association studies. METHOD: A total of 70,711 subjects from 37 independent cohorts with 13 different neuropsychiatric disorders were meta-analyzed to identify...
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