Article
ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients.
World journal of gastroenterology - 14 Mar 2014
Wolfkamp Simone C S, Verseyden Caroline, Vogels Esther W M, Meisner Sander, Boonstra Kirsten, Peters Charlotte P, Stokkers Pieter C F, te Velde Anje A
Abstract excerpt
AIM: To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn's disease (CD). METHODS: In this study, we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and granulocytes in inflammatory bowel disease patients as...
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