Article
Dissecting the causal genetic mechanisms of coronary heart disease.
Current atherosclerosis reports - 1 May 2014
Miller Clint L, Assimes Themistocles L, Montgomery Stephen B, Quertermous Thomas
Abstract excerpt
Large-scale genome-wide association studies (GWAS) have identified 46 loci that are associated with coronary heart disease (CHD). Additionally, 104 independent candidate variants (false discovery rate of 5 %) have been identified (Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Nat Genet 43:333-8, 2011; Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR et al. Nat...
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