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Article

Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation.

Hormones & cancer - 1 Jun 2014

Rapizzi Elena, Ercolino Tonino, Fucci Rossella, Zampetti Benedetta, Felici Roberta, Guasti Daniele, Morandi Andrea, Giannoni Elisa, Giaché Valentino, Bani Daniele, Chiarugi Alberto, Mannelli Massimo

Abstract excerpt

Paragangliomas (PGLs) are rare neuroendocrine tumours. About 30-40 % of these tumours are mutated in one of the different susceptibility genes, including those encoding the different subunits of the succinate dehydrogenase, a complex involved both in the tricarboxylic acid cycle and in the oxygen transport chain. The aim of this work was to investigate whether SDHB mutations may account for alterations in cell...

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Identifiers

PMID: 24595825
DOI: 10.1007/s12672-014-0172-3
PMCID: PMC10358172

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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