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Article

Association of rs2075575 and rs9951307 polymorphisms of AQP-4 gene with leukoaraiosis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jan 2000

Yadav Binod K, Oh Sun-Young, Kim Nam-Keun, Shin Byoung-Soo

Abstract excerpt

BACKGROUND: Leukoaraiosis (LA) is associated with structural and functional vascular changes that correlate with motor and gait disturbances, depressive symptoms, urinary disturbances, and dementia. The blood-brain barrier (BBB) plays a key role in development of lacunar stroke, leukoaraiosis, and other feature of cerebral small-vessel disease, and there are numerous studies examining changes in the BBB with...

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PMID: 24582793
DOI: 10.1016/j.jstrokecerebrovasdis.2013.10.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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