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Article

The effects of noncoding aquaporin‐4 single‐nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease

26 May 2017

Abstract excerpt

Abstract Introduction The glymphatic system is a brain‐wide perivascular network that facilitates clearance of proteins, including amyloid β, from the brain interstitium through the perivascular exchange of cerebrospinal fluid and interstitial fluid. The astrocytic water channel aquaporin‐4 (AQP4) is required for glymphatic system function, and impairment of glymphatic function in the aging brain is associated...

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Identifiers

PMID: 29067342
DOI: 10.1016/j.trci.2017.05.001

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The effects of noncoding aquaporin‐4 single‐nucleotide polymorphisms on cognition and functional progression of Alzheimer's diseasePMID 29067342Read ↗

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