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Article

Single-Nucleotide Polymorphisms of Tight Junction Component Claudin-1 Associated with Leukoaraiosis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jul 2015

Yadav Binod Kumar, Shin Byoung-Soo

Abstract excerpt

BACKGROUND: The blood-brain barrier (BBB) plays a major role in the development of leukoaraiosis (LA). The junctional complex of BBB consists of tight junction (TJ) and adherens junction (AJ). Claudin-1 is the integral component of TJ. The aim of this study was to evaluate whether genetic variations in claudin-1 gene are associated with the development of LA. METHODS: LA has to be diagnosed based on images. A...

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PMID: 25956626
DOI: 10.1016/j.jstrokecerebrovasdis.2015.03.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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