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Article

Analysis of genetic polymorphisms associated with leukoaraiosis in the southern Chinese population: A case-control study.

Medicine - 1 Aug 2016

Huang Wen-Qing, Ye Hui-Ming, Li Fang-Fang, Yi Ke-Hui, Zhang Ya, Cai Liang-Liang, Lin Hui-Nuan, Lin Qing, Tzeng Chi-Meng

Abstract excerpt

Leukoaraiosis (LA) is a frequent neuroimaging finding commonly observed on brain MRIs of elderly people with prevalence ranging from 50% to 100%. Multiple susceptibility genes or genetic risk factors for LA have been identified in subjects of European descent. Here, we report the first replication study on several common and novel genetic variations in the Chinese population. In this study, a total of 244...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27583843
DOI: 10.1097/MD.0000000000003857
PMCID: PMC5008527

Genes

FBF1
MTHFR
TRIM47
TRIM65
PMF1

Variants

rs3744028
rs3744028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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