Article
A homozygous genetic variant of mitochondrial uncoupling protein 4 affects the occurrence of leukoaraiosis.
Acta neurologica Scandinavica - 1 May 2011
Szolnoki Z, Kondacs A, Mandi Y, Bodor A, Somogyvari F
Abstract excerpt
OBJECTIVES: We hypothesized that an appropriate balance of the mitochondrial energy production is essential in the maintenance of the glia cells in the brain. The aim of this study was to examine the roles of the rs10807344 and rs2270450 genetic variants of mitochondrial uncoupling protein 4 in the development of vascular demyelinization of the white matter of the brain, referred to as leukoaraiosis (LA). The...
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