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Article

Association of Genetic Variation in a Wnt Signaling Pathway Gene (β-Catenin) with Susceptibility to Leukoaraiosis.

Genetic testing and molecular biomarkers - 1 Nov 2020

Yadav Binod Kumar, Yadav Renu, Kang Hyun Goo, Kim Ko Woon, Lee Chan-Hyuk, Shin Byoung-Soo

Abstract excerpt

Aim: Blood-brain barrier (BBB) disruption is the primary initiating cause of cerebral small-vessel diseases including leukoaraiosis (LA). β-Catenin is a key regulator of the BBB and plays an important role in cell-cell adhesion at adherens junctions by interacting with cadherin molecules. Thus, β-Catenin may be a good candidate gene for LA. We performed a genetic analyses to investigate the association between...

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PMID: 33026847
DOI: 10.1089/gtmb.2020.0111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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