Article
The role of aquaporin-4 polymorphisms in the development of brain edema after middle cerebral artery occlusion.
Stroke - 1 Apr 2008
Kleffner Ilka, Bungeroth May, Schiffbauer Hagen, Schäbitz Wolf-Ruediger, Ringelstein E Bernd, Kuhlenbäumer Gregor
Abstract excerpt
BACKGROUND AND PURPOSE: Some patients develop severe brain edema after complete middle cerebral artery occlusion, whereas others do not. Aquaporin-4 (AQP4) is the main water channel in the brain and has been shown to be critical for the development of brain edema after ischemia. We asked whether genetic variation in the AQP4 gene is related to the severity of brain edema after middle cerebral artery occlusion....
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