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Article

Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.

International journal of medical microbiology : IJMM - 1 May 2014

De la Fuente Marjorie, Franchi Luigi, Araya Daniela, Díaz-Jiménez David, Olivares Mauricio, Álvarez-Lobos Manuel, Golenbock Douglas, González María-Julieta, López-Kostner Francisco, Quera Rodrigo, Núñez Gabriel, Vidal Roberto, Hermoso Marcela A

Abstract excerpt

Crohn's disease (CD) is a multifactorial pathology associated with the presence of adherent-invasive Escherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in other intestinal pathologies (OIP) and the role of NLRP3-inflammasome in the immune response activated by these bacteria have not been investigated. In this study, we sought to characterize intracellular strains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24581881
DOI: 10.1016/j.ijmm.2014.01.002
PMCID: PMC4075040

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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