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Adherent-invasive Escherichia coli in inflammatory bowel disease

15 Nov 2017

Abstract excerpt

(AIEC) pathotype in particular, has been implicated in the pathogenesis of IBD. Since the discovery of AIEC, two decades ago, progress has been made in unravelling these bacteria characteristics and its interaction with the gut immune system. The mechanisms of adhesion of AIEC to intestinal epithelial cells (via FimH and cell adhesion molecule 6) and its ability to escape autophagy when inside macrophages are...

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PMID: 29141957
DOI: 10.1136/gutjnl-2017-314903

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