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Article

Defective macrophage handling of Escherichia coli in Crohn's disease.

Journal of gastroenterology and hepatology - 1 Aug 2015

Elliott T R, Hudspith B N, Rayment N B, Prescott N J, Petrovska L, Hermon-Taylor J, Brostoff J, Boussioutas A, Mathew C G, Sanderson J D

Abstract excerpt

BACKGROUND AND AIM: Escherichia coli can be isolated from lamina propria macrophages in Crohn's disease (CD), and their intramacrophage persistence may provide a stimulus for inflammation. To further determine the contributions of macrophage dysfunction and E. coli pathogenicity to this, we aimed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25809337
DOI: 10.1111/jgh.12955

Genes

IRGM
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25809337-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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