Article

Characterising molecular mechanisms of Crohn's disease-associated Escherichia coli that enable their survival and replication within macrophages

2016-01-01

Abstract excerpt

Mucosa-associated adherent, invasive Escherichia coli (AIEC), found in increased number in Crohn’s disease (CD) ileal and colonic mucosae, can survive and replicate within underlying host immune competent cells (e.g. macrophages and dendritic cells) without triggering host cell death. The intra-macrophage environment plays an essential role in bacterial killing where engulfed bacteria are exposed to a hostile envi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bcf97c6c-fab6-5c72-a4af-bc76f7531752
DOI: 10.17638/03007136

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterising molecular mechanisms of Crohn's disease-associated Escherichia coli that enable their survival and replication within macrophagesDOI 10.17638/03007136Read

E. coli associated with Crohn’s disease exhibit distinct strategies to colonize macrophagesSemantic proximity Read

The Crohn’s disease-related AIEC strain LF82 assembles a biofilm-like matrix to protect intracellular microcolonies from phagolysosomal attackSemantic proximity Read

The Crohn’s disease-associated Escherichia coli strain LF82 rely on SOS and stringent responses to survive, multiply and tolerate antibiotics within macrophagesSemantic proximity Read

Escherichia coli pathobionts and Crohn's disease: varied genetic paths leading to similar phenotypes.Semantic proximity Read

Defective macrophage handling of Escherichia coli in Crohn's disease.Semantic proximity Read

Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.Semantic proximity Read

Adherent-invasive Escherichia coli in Crohn’s disease: the 25th anniversarySemantic proximity Read

Clinical isolates of Enterobacter species can persist in human macrophages without bacterial replication and minimal cellular cytotoxicitySemantic proximity Read

HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease.Semantic proximity Read

Comparative study of pathogenic and non-pathogenic Escherichia coli outer membrane vesicles and prediction of host-interactions with TLR signaling pathwaysSemantic proximity Read

Strategies Used by Bacteria to Grow in MacrophagesSemantic proximity Read

Genomic and Phenomic Study of Mammary Pathogenic Escherichia coli.Semantic proximity Read