Article
Adherent-invasive Escherichia coli (AIEC) in pediatric Crohn's disease patients: phenotypic and genetic pathogenic features.
BMC research notes - 22 Oct 2014
Conte Maria Pia, Longhi Catia, Marazzato Massimiliano, Conte Antonietta Lucia, Aleandri Marta, Lepanto Maria Stefania, Zagaglia Carlo, Nicoletti Mauro, Aloi Marina, Totino Valentina, Palamara Anna Teresa, Schippa Serena
Abstract excerpt
BACKGROUND: Adherent-invasive Escherichia coli (AIEC) have been implicated in the ethiopathogenesis of Crohn's disease (CD). In this study, we analyzed a collection of intestinal mucosa-associated E. coli isolates, presenting AIEC phenotypes, isolated from biopsies of CD pediatric patients and non-inflammatory bowel diseases (IBD) controls, in order to investigate their genetic and phenotypic pathogenic features....
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