Article
Virulence determinants and genetic diversity of adherent-invasive Escherichia coli (AIEC) strains isolated from patients with Crohn's disease.
Microbial pathogenesis - 1 Aug 2020
Abdelhalim Khalid A, Uzel Ataç, Gülşen Ünal Nalan
Abstract excerpt
BACKGROUND: Adherent invasive Escherichia coli (AIEC) are implicated in the pathogenesis of inflammatory bowel diseases (IBD) particularly Crohn's disease (CD). The aim of this study is to isolate, identify, genotype, and characterize the virulence factors and the clinical significance of AIEC strains. METHODS: Ileal and colonic biopsies from 24 active CD patients and 15 healthy controls (HC) were collected. E....
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