Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Random monoallelic gene expression increases upon embryonic stem cell differentiation.

Developmental cell - 24 Feb 2014

Eckersley-Maslin Mélanie A, Thybert David, Bergmann Jan H, Marioni John C, Flicek Paul, Spector David L

Abstract excerpt

Random autosomal monoallelic gene expression refers to the transcription of a gene from one of two homologous alleles. We assessed the dynamics of monoallelic expression during development through an allele-specific RNA-sequencing screen in clonal populations of hybrid mouse embryonic stem cells (ESCs) and neural progenitor cells (NPCs). We identified 67 and 376 inheritable autosomal random monoallelically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes

Share to DNA Methylation

Share to Embryonic Stem Cells

Share to Gene Expression

Share to Mice, Inbred C57BL

Share to Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 24576421
DOI: 10.1016/j.devcel.2014.01.017
PMCID: PMC3955261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Random monoallelic gene expression increases upon embryonic stem cell differentiation.PMID 24576421Read ↗

Autosomal monoallelic expression in the mouse.Semantic proximity Read ↗

Locus specific epigenetic modalities of random allelic expression imbalance.Semantic proximity Read ↗

Locus specific epigenetic modalities of random allelic expression imbalanceSemantic proximity Read ↗

Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells.Semantic proximity Read ↗

Widespread monoallelic expression on human autosomes.Semantic proximity Read ↗

Random monoallelic expression: regulating gene expression one allele at a time.Semantic proximity Read ↗

Stochastic choice of allelic expression in human neural stem cells.Semantic proximity Read ↗

Monoallelic Gene Expression: Stochastic or Clonal? From Detection to Mechanisms and Clinical Significance.Semantic proximity Read ↗

Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells.Semantic proximity Read ↗

Random monoallelic expression of genes on autosomes: Parallels with X-chromosome inactivation.Semantic proximity Read ↗

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.Semantic proximity Read ↗

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.