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Article

Stochastic choice of allelic expression in human neural stem cells.

Stem cells (Dayton, Ohio) - 1 Sept 2012

Jeffries Aaron R, Perfect Leo W, Ledderose Julia, Schalkwyk Leonard C, Bray Nicholas J, Mill Jonathan, Price Jack

Abstract excerpt

Monoallelic gene expression, such as genomic imprinting, is well described. Less well-characterized are genes undergoing stochastic monoallelic expression (MA), where specific clones of cells express just one allele at a given locus. We performed genome-wide allelic expression assessment of human clonal neural stem cells derived from cerebral cortex, striatum, and spinal cord, each with differing genotypes. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22714879
DOI: 10.1002/stem.1155

Genes

OLIG2
OTX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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