Article
Random monoallelic expression of genes on autosomes: Parallels with X-chromosome inactivation.
Seminars in cell & developmental biology - 1 Aug 2016
Gendrel Anne-Valerie, Marion-Poll Lucile, Katoh Kimiko, Heard Edith
Abstract excerpt
Genes are generally expressed from their two alleles, except in some particular cases such as random inactivation of one of the two X chromosomes in female mammals or imprinted genes which are expressed only from the maternal or the paternal allele. A lesser-known phenomenon is random monoallelic expression (RME) of autosomal genes, where genes can be stably expressed in a monoallelic manner, from either one of...
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