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Random monoallelic expression of genes on autosomes: Parallels with X-chromosome inactivation.

Seminars in cell & developmental biology - 1 Aug 2016

Gendrel Anne-Valerie, Marion-Poll Lucile, Katoh Kimiko, Heard Edith

Abstract excerpt

Genes are generally expressed from their two alleles, except in some particular cases such as random inactivation of one of the two X chromosomes in female mammals or imprinted genes which are expressed only from the maternal or the paternal allele. A lesser-known phenomenon is random monoallelic expression (RME) of autosomal genes, where genes can be stably expressed in a monoallelic manner, from either one of...

Topics

Alleles
Animals
Chromosomes
Disease
Humans
Single-Cell Analysis
X Chromosome Inactivation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27101886
DOI: 10.1016/j.semcdb.2016.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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