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Article

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

Drug metabolism and disposition: the biological fate of chemicals - 1 May 2014

Hu Dong Gui, Meech Robyn, Lu Lu, McKinnon Ross A, Mackenzie Peter I

Abstract excerpt

Identification of functional polymorphisms in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene predicting interpatient variability in the glucuronidation of drugs that are primarily metabolized by UGT2B7 has been the subject of many studies. These studies have shown linkage disequilibrium (LD) covering the region from -2 kb to 16 kb of the UGT2B7 gene. We identified three novel single-nucleotide polymorphisms...

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PMID: 24561451
DOI: 10.1124/dmd.113.056630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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