Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.

Human mutation - 1 Jul 2006

Thomas Sushma S, Li Shuying S, Lampe Johanna W, Potter John D, Bigler Jeannette

Abstract excerpt

UDP-Glucuronosyltransferases (UGTs) are a superfamily of enzymes responsible for glucuronidation of xenobiotics and endobiotics. Genetic polymorphisms have been identified in the promoter and exonic regions of several UGT genes. The UGT1As on chromosome 2q37 have unique exons 1 but share the remainder of their coding sequence. We screened exon 1 of each of the nine functional UGT1As in Asians (n=46) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Exons
Share to Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Multigene Family

Share to Promoter Regions, Genetic

Share to White People

Source

Identifiers

PMID: 16786511
DOI: 10.1002/humu.9432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.PMID 16786511Read ↗

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.Semantic proximity Read ↗

Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.Semantic proximity Read ↗

Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.Semantic proximity Read ↗

Common genetic polymorphisms in the 5'-flanking region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity.Semantic proximity Read ↗

Functional Study of Haplotypes in UGT1A1 Promoter to Find a Novel Genetic Variant Leading to Reduced Gene Expression.Semantic proximity Read ↗

UGT1A polymorphisms in a Swedish cohort and a human diversity panel, and the relation to bilirubin plasma levels in males and females.Semantic proximity Read ↗

Haplotype structures of the UGT1A gene complex in a Japanese population.Semantic proximity Read ↗

Comprehensive variant screening of the UGT gene family.Semantic proximity Read ↗

Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.Semantic proximity Read ↗

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.Semantic proximity Read ↗

Differences in frequencies of UGT1A9, 1A7, and 1A1 genetic polymorphisms in Chinese Tibetan versus Han Chinese populations.Semantic proximity Read ↗

Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.