Article
Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.
Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2004
Saeki Mayumi, Saito Yoshiro, Jinno Hideto, Tanaka-Kagawa Toshiko, Ohno Akiko, Ozawa Shogo, Ueno Kazuyuki, Kamakura Shiro, Kamatani Naoyuki, Komamura Kazuo, Kitakaze Masafumi, Sawada Jun-Ichi
Abstract excerpt
Both UDP-glucuronosyltransferase 2B4 (UGT2B4) and UGT2B7 are expressed mainly in the human liver and have several overlapping substrates; e.g., catechol estrogens, bile acids, codeine, and carvedilol. To identify novel single nucleotide polymorphisms (SNPs) and haplotypes in a Japanese population...
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