Article
Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation.
Journal of hepatology - 1 Jun 2014
Eickmeier Ira, Seidel Daniel, Grün Joachim R, Derkow Katja, Lehnardt Seija, Kühl Anja A, Hamann Alf, Schott Eckart
Abstract excerpt
BACKGROUND & AIMS: The enterohepatic circuit of T cells may be responsible for the development of autoimmune liver disease. We employed transgenic mice to characterize phenotype and migration patterns of CD8 T cells activated in liver and gut. METHODS: We studied the migration of antigen-specific CD8 T cells primed in liver or gut after transfer in wild-type mice or mice that express ovalbumin in liver or gut. We...
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