Article

Antigen-driven CD8 <sup>+</sup> T cell clonal expansion is a prominent feature of MASH in humans and mice

2024-03-22

Abstract excerpt

<h4>Background and Aims</h4> Chronic liver disease due to metabolic dysfunction-associated steatohepatitis (MASH) is a rapidly increasing global epidemic. MASH progression is a consequence of the complex interplay between inflammatory insults and dysregulated hepatic immune responses. T lymphocytes have been shown to accumulate in the liver during MASH, but the cause and consequence of T cell accumulation in the...

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Literature Corpus work: 61e93375-e594-5bcf-bb0d-ca956a20f284
DOI: 10.1101/2024.03.20.583964

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