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Article

IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2013

Tang Xin-Zi, Jo Juandy, Tan Anthony T, Sandalova Elena, Chia Adeline, Tan Kai Chah, Lee Kang Hoe, Gehring Adam J, De Libero Gennaro, Bertoletti Antonio

Abstract excerpt

Human mucosal-associated invariant T (MAIT) cells are a T cell population characterized by the expression of a semi-invariant TCR capable of recognizing bacterial products in the context of MR1. MAIT cells are enriched in the human liver, which is constantly exposed to bacterial products from the intestine. Whether this specific parenchymal localization influences their function remains unknown. We analyzed MAIT...

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Identifiers

PMID: 23447689
DOI: 10.4049/jimmunol.1203218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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