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Article

Highly efficient and specific genome editing in silkworm using custom TALENs.

PloS one - 1 Jan 2012

Ma Sanyuan, Zhang Shengling, Wang Feng, Liu Yong, Liu Yuanyuan, Xu Hanfu, Liu Chun, Lin Ying, Zhao Ping, Xia Qingyou

Abstract excerpt

Establishment of efficient genome editing tools is essential for fundamental research, genetic engineering, and gene therapy. Successful construction and application of transcription activator-like effector nucleases (TALENs) in several organisms herald an exciting new era for genome editing. We describe the production of two active TALENs and their successful application in the targeted mutagenesis of silkworm,...

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Identifiers

PMID: 23028749
DOI: 10.1371/journal.pone.0045035
PMCID: PMC3445556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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