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Article

FLASH assembly of TALENs for high-throughput genome editing.

Nature biotechnology - 1 May 2012

Reyon Deepak, Tsai Shengdar Q, Khayter Cyd, Foden Jennifer A, Sander Jeffry D, Joung J Keith

Abstract excerpt

Engineered transcription activator–like effector nucleases (TALENs) have shown promise as facile and broadly applicable genome editing tools. However, no publicly available high-throughput method for constructing TALENs has been published, and large-scale assessments of the success rate and targeting range of the technology remain lacking. Here we describe the fast ligation-based automatable solid-phase...

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Identifiers

PMID: 22484455
DOI: 10.1038/nbt.2170
PMCID: PMC3558947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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