Article
Metformin resistance alleles in polycystic ovary syndrome: pattern and association with glucose metabolism.
Pharmacogenomics - 1 Feb 2014
Schweighofer Natascha, Lerchbaum Elisabeth, Trummer Olivia, Schwetz Verena, Pieber Thomas, Obermayer-Pietsch Barbara
Abstract excerpt
Insulin-sensitizer treatment with metformin is common in polycystic ovary syndrome (PCOS). OCT alleles were investigated in PCOS patients to identify genetic 'bad responders' and 'nonresponders' to metformin including their possible effects on glucose metabolism without treatment. We genotyped ei...
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