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The Influence of OCT3 and MATE2 Genetic Polymorphisms in Poor Response to Metformin in Type 2 Diabetes Mellitus.

Endocrinology, diabetes & metabolism - 1 Sept 2024

Naem Alaa Abd Al-Hussain, Al-Terehi Mona N, Ghafil Fadhaa Abdulameer, Ataya Farid S, Batiha Gaber El-Saber, Alexiou Athanasios, Papadakis Marios, Welson Nermeen N, Hadi Najah R

Abstract excerpt

BACKGROUND: The response of patients with Type 2 diabetes mellitus (T2DM) to metformin may be a variation because of genetic differences in solute carrier (SLC) transporter proteins and other effect factors, which have an important effect on how metformin is processed in the body and its efficiency for glycaemic control. AIM: This study was conducted to investigate the impact of certain genetic variants of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39086121
DOI: 10.1002/edm2.486
PMCID: PMC11291545

Genes

SLC22A3
SLC47A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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The Influence of OCT3 and MATE2 Genetic Polymorphisms in Poor Response to Metformin in Type 2 Diabetes Mellitus.PMID 39086121Read ↗

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