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Article

The Pharmacogenetics of Metformin in Women with Polycystic Ovary Syndrome: A Randomized Trial

21 Aug 2017

Abstract excerpt

Abstract Polycystic ovary syndrome ( PCOS ) is the most common endocrine disorder affecting women of reproductive age. PCOS is associated with obesity, dyslipidaemia and insulin resistance, and metformin treatment may improve such metabolic features. The effect of genetic variants in key metformin transporters, their transcriptional regulators or in metformin target genes on metformin response in women with PCOS...

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PMID: 28834135
DOI: 10.1111/bcpt.12874

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