Back to search

Article

Association of Single Nucleotide Polymorphism in OCT1 and OCT3 Genes with the Efficacy of Metformin Response in North Indian Type 2 Diabetes Mellitus Patients.

2023-08-09

Abstract excerpt

<h4>Purpose: </h4> Interindividual variation in efficacy of metformin among type 2 diabetes mellitus (T2DM) patients have been associated with several genetic variants. Understanding the genetic pathways involved in pharmacodynamics of metformin can affect personalized treatment of T2DM. Our study aimed to find the implication of genetic polymorphism in organic cation transporters ( OCT1 and OCT3) genes on drug ef...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bd4e0523-e6cb-5241-a100-2fc33834cb7d
DOI
10.21203/rs.3.rs-3227562/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Association of Single Nucleotide Polymorphism in OCT1 and OCT3 Genes with the Efficacy of Metformin Response in North Indian Type 2 Diabetes Mellitus Patients.DOI 10.21203/rs.3.rs-3227562/v1
Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol.Semantic proximity
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin.Semantic proximity
The Influence of OCT3 and MATE2 Genetic Polymorphisms in Poor Response to Metformin in Type 2 Diabetes Mellitus.Semantic proximity
Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review.Semantic proximity
The influence of SLC22A3 rs543159 and rs1317652 genetic variants on metformin therapeutic efficacy in newly diagnosed patients with type 2 diabetes mellitus: 25 weeks follow-up study.Semantic proximity
A Review of the Impact of Pharmacogenetics and Metabolomics on the Efficacy of Metformin in Type 2 DiabetesSemantic proximity
Influence of GLUT2 rs8192675, MATE1 rs2289669, and OCT2 rs316019 Genetic Polymorphism on Metformin Efficacy and Glycemic Control in Type 2 Diabetes Mellitus PatientsSemantic proximity
Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes.Semantic proximity
Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.Semantic proximity
Effects of genetic variants of organic cation transporters on metformin response in newly diagnosed patients with type 2 diabetes.Semantic proximity
Association between organic cation transporter genetic polymorphisms and metformin response and intolerance in T2DM individuals: a systematic review and meta-analysis.Semantic proximity
Metformin efficacy and tolerance according to genetic polymorphisms of organic cation transporter 1 in Tunisian patients with type 2 diabetesSemantic proximity
Select a neighboring publication to make it the new centre.