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Article

CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease.

Journal of the neurological sciences - 15 Apr 2014

Chung Sun Ju, Kim Mi-Jung, Kim Young Jin, Kim Juyeon, You Sooyeoun, Jang Eun Hye, Kim Seong Yoon, Lee Jae-Hong

Abstract excerpt

BACKGROUND: The genetic factors that determine the heterogeneity of cognitive impairment in Alzheimer's disease (AD) patients have been rarely reported. We aimed to investigate the association between top hits of genome-wide association studies (GWAS) and specific cognitive domains in AD patients. METHODS: We investigated 86 single nucleotide polymorphisms (SNPs) selected from 12 genes (ABCA7, APOE, BIN1, CD2AP,...

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Source

Identifiers

PMID: 24530172
DOI: 10.1016/j.jns.2014.01.029

Genes

ABCA7
APOE
BIN1
CLU
EPHA1
LRAT
PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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