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Article

Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.

PloS one - 1 Jan 2012

Karch Celeste M, Jeng Amanda T, Nowotny Petra, Cady Janet, Cruchaga Carlos, Goate Alison M

Abstract excerpt

Late onset Alzheimer's disease (LOAD) etiology is influenced by complex interactions between genetic and environmental risk factors. Large-scale genome wide association studies (GWAS) for LOAD have identified 10 novel risk genes: ABCA7, BIN1, CD2AP, CD33, CLU, CR1, EPHA1, MS4A6A, MS4A6E, and PICALM. We sought to measure the influence of GWAS single nucleotide polymorphisms (SNPs) and gene expression levels on...

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Source

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Identifiers

PMID: 23226438
DOI: 10.1371/journal.pone.0050976
PMCID: PMC3511432

Genes

ABCA7
BIN1
CLU
EPHA1
PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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