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Article

ABCA7 p.G215S as potential protective factor for Alzheimer's disease.

Neurobiology of aging - 1 Oct 2016

Sassi Celeste, Nalls Michael A, Ridge Perry G, Gibbs Jesse R, Ding Jinhui, Lupton Michelle K, Troakes Claire, Lunnon Katie, Al-Sarraj Safa, Brown Kristelle S, Medway Christopher, Clement Naomi, Lord Jenny, Turton James, Bras Jose, Almeida Maria R, Holstege Henne, Louwersheimer Eva, van der Flier Wiesje M, Scheltens Philip, Van Swieten John C, Santana Isabel, Oliveira Catarina, Morgan Kevin, Powell John F, Kauwe John S, Cruchaga Carlos, Goate Alison M, Singleton Andrew B, Guerreiro Rita, Hardy John

Abstract excerpt

Genome-wide association studies (GWASs) have been effective approaches to dissect common genetic variability underlying complex diseases in a systematic and unbiased way. Recently, GWASs have led to the discovery of over 20 susceptibility loci for Alzheimer's disease (AD). Despite the evidence showing the contribution of these loci to AD pathogenesis, their genetic architecture has not been extensively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27289440
DOI: 10.1016/j.neurobiolaging.2016.04.004
PMCID: PMC5024078

Genes

ABCA7
APOE
BIN1
CLU
EPHA1
PICALM

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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