Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

A Meta-Analysis of Brain-Derived Neurotrophic Factor Effects on Brain Volume in Schizophrenia: Genotype and Serum Levels.

Neuropsychobiology - 1 Jan 2021

Ahmed Anthony O, Kramer Samantha, Hofman Naama, Flynn John, Hansen Marie, Martin Victoria, Pillai Anilkumar, Buckley Peter F

Abstract excerpt

AIM: The Val66Met single-nucleotide polymorphism (SNP) on the BDNF gene has established pleiotropic effects on schizophrenia incidence and morphologic alterations in the illness. The effects of brain-derived neurotrophic factor (BDNF) on brain volume measurements are however mixed seeming to be less established for most brain regions. The current meta-analytic review examined (1) the association of the Val66Met...

Topics

Brain
Brain-Derived Neurotrophic Factor
Genotype
Hippocampus
Humans
Polymorphism, Single Nucleotide
Schizophrenia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33706323
DOI: 10.1159/000514126
PMCID: PMC8619762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Meta-Analysis of Brain-Derived Neurotrophic Factor Effects on Brain Volume in Schizophrenia: Genotype and Serum Levels.PMID 33706323Read ↗

Effects of brain-derived neurotrophic factor Val66Met polymorphism on hippocampal volume change in schizophrenia.Semantic proximity Read ↗

BDNF Val66Met polymorphism and hippocampal volume in neuropsychiatric disorders: A systematic review and meta-analysis.Semantic proximity Read ↗

Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia.Semantic proximity Read ↗

BDNF gene variants and brain morphology in schizophrenia.Semantic proximity Read ↗

Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation.Semantic proximity Read ↗

Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia.Semantic proximity Read ↗

Reduced hippocampal volumes in healthy carriers of brain-derived neurotrophic factor Val66Met polymorphism: meta-analysis.Semantic proximity Read ↗

Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers.Semantic proximity Read ↗

Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphism and Risk of Schizophrenia: A Meta-analysis of Case-Control Studies.Semantic proximity Read ↗

A role for the BDNF gene Val66Met polymorphism in schizophrenia? A comprehensive review.Semantic proximity Read ↗

Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons.Semantic proximity Read ↗

Influence of BDNF and MTHFR polymorphisms on hippocampal volume in first-episode psychosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.